Its not complicated. There are dose response curves for everything once you start studying them - https://www.epa.gov/environmental-topics/chemicals-and-toxics

Its not complicated. There are dose response curves for everything once you start studying them - https://www.epa.gov/environmental-topics/chemicals-and-toxics-topics https://www.epa.gov/environmental-topics/chemicals-and-toxic... https://www.epa.gov/fera/dose-response-assessment-assessing-health-risks-associated-exposure-hazardous-air-pollutants https://www.epa.gov/fera/dose-response-assessment-assessing-... How did we build these tables? Same process will apply to how much dopamine (and whatever else) you can keep giving a kid or a group of people over time without serious consequences Whether that takes 2 years or 20 years more to tabulate, lots of people will take a hit thanks to their internal reward mechanisms being gamed.