I wrote this whole long comment talking about all the issues in trying to design a good trial to figure this out, but here's one trial I think will give us some

I wrote this whole long comment talking about all the issues in trying to design a good trial to figure this out, but here's one trial I think will give us some more info, it seems better designed than the other ones I've seen (sample size remains a problem): https://clinicaltrials.gov/ct2/show/NCT04525820 https://clinicaltrials.gov/ct2/show/NCT04525820