3 ms·
"Instead, our focus should shift to ensuring appropriate antibiotic use as well as improving dialogue with prescribers and patients about the harms of antibioti
by avmich 6y ago
"Instead, our focus should shift to ensuring appropriate antibiotic use as well as improving dialogue with prescribers and patients about the harms of antibiotic overuse."
Quite an unclear statement and the article as a whole. Article explains well why "finish the course" could be the right thing - Fleming's Nobel lecture is brought as illustration - but then fails explaining how and why this "finishing" is wrong.
- rossdavidh 6y ago"Additionally, long durations of therapy put patients at increased risk for adverse effects,16,17 including the development of Clostridium difficile infection,18 which is associated with significant morbidity and mortality." 16. Milo G, Katchman E, Paul M, et al. Duration of antibacterial treatment for uncomplicated urinary tract infection in women. Cochrane Database Syst Rev 2005;2:CD004682. [PubMed] [Google Scholar] 17. Vogel T, Verreault R, Gourdeau M, et al. Optimal duration of antibiotic therapy for uncomplicated urinary tract infection in older women: a double-blind randomized controlled trial. CMAJ 2004;170(4): 469-73. [PMC free article] [PubMed] [Google Scholar] 18. Owens RC, Donskey CJ, Gaynes RP, et al. Antimicrobial-associated risk factors for Clostridium difficile infection. Clin Infect Dis 2008;46:S19-31. [PubMed] [Google Scholar]