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> Yes, with the control group you would have a base for how many people you would have expected to be infected, so there's that, but you "could" get that from o
by ilyagr 6y ago
> Yes, with the control group you would have a base for how many people you would have expected to be infected, so there's that, but you "could" get that from other observations.
Getting this number for a distribution of people as similar as possible to the people in the experimental group is, in fact, the primary purpose of having a control group. There is no better way to predict this number, as you can't predict how likely a particular person is to catch coronavirus at a particular time, in a particular location.
You also need a control group to get the number of various medical problems expected in the experimental group, even if the vaccine doesn't cause them. This also depends on time, place, and behavior.
So, if you create a reason for people in the control group to behave differently from experimental group, for instance by letting people find out which group they are in, you defeat the purpose of having a control group.
- raverbashing 6y agoThanks for your answer I'm not denying there's the need for a baseline to compare to, but the need to have an dedicated designated group to be the 'official control'. I agree it makes things easier statistically. > So, if you create a reason for people in the control group to behave differently from experimental group Yes and here lies a minor catch, both those groups might behave differently from the population in general (even though they aren't "supposed to")