3 ms·

I haven't read this bioRxiv paper, but what's the difference between it and this Cell paper from 2017? https://pubmed.ncbi.nlm.nih.gov/28575667/ https://pubmed

• mattkrause 6y ago
  "Deep" in the mouse is a few millimeters, while deep brain structures in primates are 10-15x deeper. In primates, the fields would be harder to precisely interfere because of our thicker skulls and larger, more convoluted brains. The level of c-fos activation in the Cell paper is also a little crazy--it seems way too intense to be correct, especially when compared against direct electrophysiological measurements. It's also not 100% clear that the high frequency fields do nothing--there are some claims that they have DC-like effects due to hysteresis in the neurons' membrane potentials.
  • whymauri 6y ago
    Oh snap, I didn't notice the animal model changed. Thanks for the heads up and rundown!