> I would have thought you’d give a risky new drug to the least healthy Yes, but at this stage there is no drug. You're in the process of making the drug. And

> I would have thought you’d give a risky new drug to the least healthy Yes, but at this stage there is no drug. You're in the process of making the drug. And you don't want to test your beta versions on sensitive subjects. Once nothing obviously bad happens, you can expand the test circle.