Oh absolutely, they picked a model system that is both very rigid and has extremely high internal symmetry, and I assume they did rotational averaging to use fe

Oh absolutely, they picked a model system that is both very rigid and has extremely high internal symmetry, and I assume they did rotational averaging to use fewer images. But these ideal systems are very useful for determining the limitations of the underlying technology like electron detectors; 15 years ago the best you could do with a molecule like this was around 4 Angstrom resolution.