UP doesn't really apply here. The data the underlies the reconstructions requires massive averaging of individual objects as part of the tomography (see Radon t

UP doesn't really apply here. The data the underlies the reconstructions requires massive averaging of individual objects as part of the tomography (see Radon transform for the core approach). In addition those objects/particles need to have the requisite symmetry/similarity/regularity in structure (not universally applicable), or the population of them needs to be completely homogeneous (hard to achieve). I suspect that there are now better techniques for detecting outliers so homogeneity might not be as important.