>Isn't frequent LSD usage not good for the heart? Surprised there's nothing mentioned about it. IIRC (I haven't done LSD since 1987, although I used it quite a

>Isn't frequent LSD usage not good for the heart? Surprised there's nothing mentioned about it. IIRC (I haven't done LSD since 1987, although I used it quite a bit before then), it's not so much that LSD has an impact on the heart, it's the speed (methamphetamine) that's often added to LSD that can negatively impact heart function. In fact, I don't recall any issues with tachycardia when using "clean" LSD, while that wasn't unusual on LSD with speed. I'd add that negative interactions while under the influence of LSD (i.e., 'bad' trip) can certainly cause some tachycardia, as that circumstance can cause anxiety and fear. However, as long as one remains in a supportive, positive atmosphere, that's generally not an issue. I did a cursory look around and found this study[0] from July 2020 which did mention tachycardia in passing, but notes that: "LSD use can lead to hypothermia, piloerection, tachycardia with palpitation, an elevation of blood pressure, and hyperglycemia. The autonomic reactions listed above are not as significant as the mental and behavioral effects of LSD on the body." However, it's not clear whether those responses were observed or self-reported. This is important since, as I mentioned, LSD is often (by those vending it, rather than end users) "enhanced" with methamphetamine and it's also unclear whether or not such responses are limited to 'bad trips' or not. All that said, my experience is (obviously) anecdotal. If there are other studies (sadly, since LSD is a Schedule 1[1] substance, studying its effects is rare, at least in the US) with more direct observations, I'd love to see them. [0] https://www.ncbi.nlm.nih.gov/books/NBK482407/ https://www.ncbi.nlm.nih.gov/books/NBK482407/ [1] https://www.dea.gov/drug-scheduling https://www.dea.gov/drug-scheduling