3 ms·
Like Propofol ???. Don't it just turn on the chlorine tap on a neuron to open so that the voltage is now much lower and it will inhibit the signaling ???. It
by tibbydudeza 6y ago
Like Propofol ???.
Don't it just turn on the chlorine tap on a neuron to open so that the voltage is now much lower and it will inhibit the signaling ???.
It is the natural mechanism of a neuron so I don't see what side effects there could be - it is like pulling a jumper wire from one pin to another pin on a board to get a voltage right.
- jac241 6y agoGreat point and I see that commenters above are suggesting conscious sedation (benzos) instead of general, which would probably be propofol in this case. Both benzos and propofol act at the same chloride channel...
- sharru-in 6y agoI’m an emergency physician and we use all of the above medications with the exception of general anesthesia. Benzodiazepines are considerate anxiolytics whereas propofol would be considered moderate sedation. Neither of these require airway control (intubation) because people tend to keep breathing on their own and we really would much prefer that. With general anesthesia, you cannot protect your airway whatsoever and will need some form of airway control via either endotracheal intubation or LMA.
- jac241 6y agoThank you for the knowledge. I'm an M3 who hasn't had surgery, EM, or anesthesia rotations yet. Probably should have thought about the airway though...
- seehafer 6y agoIn most procedures I've observed (or experienced first-hand), a combo of Versed (a benzo) and a small amount of Propofol for the "milk of amnesia" effect is lumped under the term "conscious sedation". The patient is aware, can breathe on their own, and can respond to basic commands, but is relaxed, with a much higher pain threshold, and has no memory of the event. That sync with your experience, doc?