4 ms·
Propofol is definitely used as one of probably a cocktail of drugs required for various levels of sedation (AKA “general anesthesia” in this case). I’ve experi
by brodie 6y ago
Propofol is definitely used as one of probably a cocktail of drugs required for various levels of sedation (AKA “general anesthesia” in this case).
I’ve experienced the exact same pain you’re talking about but with IV antibiotics. No nurse or doctor could actually explain why it was happening to me, other than to say the IV had “gone bad.” Because I was in the hospital for so long, they eventually switched me to a PICC line. Absolutely zero pain with that.
My own experiences with propofol involved either the PICC line, or maybe some kind of arterial line or something (I was unconscious when I was first sedated during this incident).
- azalemeth 6y agoProbably local phlebitis. Propofol is a milky emulsion and is very lipid soluble (that's what makes it a good, blood-brain-barrier crossing agent!) but occasionally does cause side effects [1] --- I understand, particularly if it gets outside of the vessel at all. [1] https://www.jaci-inpractice.org/article/S2213-2198(19)30762-7/abstract https://www.jaci-inpractice.org/article/S2213-2198(19)30762-...
- JshWright 6y agoThere can be a number of things covered by the phrase "gone bad", ranging from phlebitis (inflammation of the vein) to infiltration (where the catheter becomes dislodged from the vein (or pokes through it)) and the IV fluid leaks into the surrounding tissue.