I'm not saying you're wrong, but last I checked (admittedly, years ago) there was at least 1 Python JIT with a lot of development and user hours behind it, with

I'm not saying you're wrong, but last I checked (admittedly, years ago) there was at least 1 Python JIT with a lot of development and user hours behind it, with good results. Seems like that experience should yield some decent estimates on speedup.