At this point to my knowledge there is only one treatment that have been shown in an RCT trial to have a large effect: that is giving bolus dosages of vitamin D

At this point to my knowledge there is only one treatment that have been shown in an RCT trial to have a large effect: that is giving bolus dosages of vitamin D. [1] The effect was that only 1 (2%) of 50 patients needed ICU admission whereas the control had 50% ICU admission. In contrast the Remdesivir effect found was just fewer days of recovery. So we can contrast the vitamin D result with how much effort is going on to determine whether there are marginal improvements from anti-virals. The trial is small (100 participants), so we should be doing a larger one now, but I don't think there is a down-side to adopting this as a standard of care. [1] https://www.sciencedirect.com/science/article/pii/S0960076020302764?via%3Dihub https://www.sciencedirect.com/science/article/pii/S096007602...