There are much more fundamental issues with doing any research on drugs like this. First there's a huge selection issue, many won't ever want to take it. Sinc

There are much more fundamental issues with doing any research on drugs like this. First there's a huge selection issue, many won't ever want to take it. Since the drug has a strong effect you cannot easily design a placebo study - people would still know if they got a sugar pill or the real deal [0]. Anything that's a highly unusual experience is likely to be rated as significant. Very hard to design a good study. I believe the reported efficacy would greatly go down with increased availability. If alcohol was a mostly illegal schedule 1 drug in most of the world I could see similar narratives forming around it. [0] btw I think that's a very underappreciated factor across all kinds of research. Even with regular medical drugs. Don't see it brought up too much.