I'd also add that taking vitamin D cofactors is essential. Just look up any chemical database like Kegg or Reactome. Vitamin D reactions tend to consume magnes

I'd also add that taking vitamin D cofactors is essential. Just look up any chemical database like Kegg or Reactome. Vitamin D reactions tend to consume magnesium, boron, etc. Supplementing those is very important, both for effectiveness and long-term safety. I know some multiple sclerosis patients that are taking megadoses, under medical supervision. Doctors have learned that cofactors are crucial to avoid nasty side effects.