Another case-study that may be of interest has some information on effects of elevated Vitamin D levels on the kidneys: "In terms of renal involvement, hyperc

Another case-study that may be of interest has some information on effects of elevated Vitamin D levels on the kidneys: "In terms of renal involvement, hypercalcemia can cause kidney injury both acutely and chronically. Hypercalcemia can cause acute kidney injury primarily by 2 mechanisms: afferent arteriolar constriction and intravascular volume depletion from a diuretic effect through activation of calcium-sensing receptor at the sodium–chloride cotransporter in the loop of Henle." Use of vitamin D drops leading to kidney failure in a 54-year-old man Bourne L. Auguste, Carmen Avila-Casado, Joanne M. Bargman CMAJ Apr 2019, 191 (14) E390-E394; DOI: 10.1503/cmaj.180465 There's a cool histological slide showing the actual calcium deposits in the kidneys that were causing some problems. This fella had a couple other things going on as well that likely contributed to this, but food for thought.