My team is split between the US and India. The time zone difference makes things harder, but we work well together. The cultural issues are greatly lessened by

My team is split between the US and India. The time zone difference makes things harder, but we work well together. The cultural issues are greatly lessened by the fact that a number of people on the US side of the divide are from India, and I (US-born white guy) have made five trips to India to get to know people there. We're able to hand off issues to each other and address customer issues quickly because someone is available around the clock. I've had to push back and limit meetings to keep from working all the time, but it's easy to get sucked into over-long hours.