4 ms·
I wonder if this is at all related to the common pairing of citrus fruits with psychedelic drugs. A lot of people recommend eating an orange or drinking orange
by dfalzone 6y ago
I wonder if this is at all related to the common pairing of citrus fruits with psychedelic drugs. A lot of people recommend eating an orange or drinking orange juice when you take LSD, and a lot of people recommend using lemons to enhance psilocybin mushroom trips. Maybe grapefruit would pair even better with these drugs.
- cyberbanjo 6y agoGrapefruit juice also has drug interactions with opiates and (I think) anti depressants, amongst other things.
- cowboysauce 6y agoThe lemon-tek method of consuming psilocybin mushrooms isn’t related to this. Acidic conditions speed up the conversion of psilocybin into psilocin. This normally happens in your stomach, the lemon-tek method just does externally. This causes the overall experience to be shorter, but more intense. Psilocin also doesn’t appear to be metabolized by the enzymes that grapefruit inhibits.
- SirLuxuryYacht 6y agosource?
- cowboysauce 6y agoThe wikipedia article for Psilocybin has all of the above. >Psilocybin [...] is a prodrug that is converted into [...] psilocin [...] This chemical reaction takes place under strongly acidic conditions And for metabolism >Psilocin is broken down by the enzyme monoamine oxidase [...] Some psilocin is not broken down by enzymes and instead forms a glucuronide [...] Psilocin is glucuronated by the glucuronosyltransferase enzymes UGT1A9 in the liver, and by UGT1A10 in the small intestine
- TT3351 6y agoCertainly reminds me of the Kool Aid in "Electric Kool Aid Acid Test"