3 ms·
I’m wondering, why not take advantage of this and add the grapefruit furanocoumarins to drugs to make smaller doses more effective?
by surround 6y ago
I’m wondering, why not take advantage of this and add the grapefruit furanocoumarins to drugs to make smaller doses more effective?
- ricksunny 6y agoIt would be worth big pharma looking further into. I fear however they'll identify that blood serum levels of an ingested drug are variable enough as it is due to the uniqueness of humans, that actively modulating humans ability to process exogenous chemicals is a recipe for disaster. Maybe they'll even get it close to right for Drug A, but what about Drug B that any given patient is concomitantly taking?
- chorsestudios 6y agoPeople often take multiple prescription medications, doing this might complicate things. The cytochrome P450 enzymes help metabolize a very wide range of compounds.
- cowboysauce 6y agoBecause it would increase the number of medications that interact with each other. E.g. you're taking medications A and B, but now A and B come with the potentiating compounds in the pills. So taking both of them could be dangerous. You to go to the hospital and they need to give you C, but it would be dangerous because of the potentiator. It would also make medication management more difficult as people have to remember if they're taking the potentiated drug or not.