2 ms·
Thank you also for the discussion. Controlling a cell population in the body is yet another great challenge! Maybe it could be more feasible if there were two
by JPLeRouzic 6y ago
Thank you also for the discussion.
Controlling a cell population in the body is yet another great challenge!
Maybe it could be more feasible if there were two sub-systems:
1. A new virus detector, it doesn't have to be based on B cells, an implantable device could perhaps fill that role at least as a first step.
2. A platform can produce a personalized vaccine. I made a toy version of this a few years ago for peptide vaccines [0].
2.1. On the software side there are minor challenges.
2.2. On the legal aspect of a personalized vaccine, its transport and administration, it is much more complicated, those are real challenges.
[0] https://padiracinnovation.org/en/peptide_PoC/ https://padiracinnovation.org/en/peptide_PoC/
- respinal 6y agoYou are welcome! For #1, I totally agree, used B cells as an example, and also implantable devices/sensors could bring more challenges (foreign body response, encapsulation, a big issue for implantable sensors). I am thinking more of a new virus detector that can be used in vitro or outside that can automatically adapt to viral changes (mutations). Let's call it "molecular morphing" virus detector, if you will (https://www.researchgate.net/figure/Principles-of-the-molecular-morphing-approach-Molecular-morphing-generates-a-path-in_fig3_261032438 https://www.researchgate.net/figure/Principles-of-the-molecu...). For #2, sweet! Thanks for sharing! The new virus detection platform could be used to create personalized vaccines, yes. For #2.1, oh. Software can definitively do things faster like try million iterations until they find the "perfect match" or strong bond (from my previous comments) for viral spike proteins. For #2.2, also agree, I am more interested in the detection/screening side of things for diseases in general.