The thing that is ignored here is that while molecules move fast ... they go nowhere. It's a random walk. It takes 6 hours for your small protein molecule to mo

The thing that is ignored here is that while molecules move fast ... they go nowhere. It's a random walk. It takes 6 hours for your small protein molecule to move 1cm ... at 250kph. So while these molecules offering themselves up "automatically" works, it only works at very short ranges and it's a stochastic range. At 1nm they meet 100k times per second. At 1cm once per 6 hours. At 3cm once per month. So there is in fact a lot of bookkeeping, keeping things tethered where they need to be and dragging things around to be done inside the cell where everything magically happens. People in this thread aren't correct that it's not necessary to do that. You don't need to get positions exactly right, as in you don't have to get the amino acids in every ribosome, but you DO have to get them "more or less" where they need to be. If for example if the amino acid concentrations near ribosomes ever get low, that's the end of you in about 2h (there's a fungus that causes that).