3 ms·
I wonder if inducing small injuries can cause repair pathways to turn on, promoting overall healing if the initial damage was little. Like how mild exercise cau
by pazimzadeh 6y ago
I wonder if inducing small injuries can cause repair pathways to turn on, promoting overall healing if the initial damage was little. Like how mild exercise causes DNA damage which stimulates overall repair, and you can come out ahead as long as the damage isn't too great (don't exercise too much at once).
Influence of Acute Exercise on DNA Repair and PARP
Activity before and after Irradiation in Lymphocytes
from Trained and Untrained Individuals
https://sci-hub.st/10.3390/ijms20122999 https://sci-hub.st/10.3390/ijms20122999
- Confiks 6y agoThis effect is called hormesis [1] and is quite established for various kinds of stressors. For example also in the context of oxygen depriving breathing exercises and cold baths [2] (which is how I came across the term only this week). On the topic of bloodletting and blood donations, I found these interesting considerations [3]. There is a correlation of less cardiovascular disease among people who donate blood. Of course there are lots of confounding factors here. The article summarizes them nicely. [1] https://en.wikipedia.org/wiki/Hormesis https://en.wikipedia.org/wiki/Hormesis [2] https://news.ycombinator.com/item?id=24676116 https://news.ycombinator.com/item?id=24676116 [3] https://joshmitteldorf.scienceblog.com/2015/11/09/does-donating-blood-extend-your-life-expectancy/ https://joshmitteldorf.scienceblog.com/2015/11/09/does-donat...
- renewiltord 6y agoAmusingly, the high you get from spicy food is supposedly similar (I've only read this on the Internet where everyone ultimately links back to a source that isn't particularly authoritative).