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As a layman: How is immunity defined? The German virologist Drosten said in an interview (a while ago, sorry, no source) that it is expected that survivors wil

As a layman: How is immunity defined? The German virologist Drosten said in an interview (a while ago, sorry, no source) that it is expected that survivors will stop producing white blood cells at some point. The next time they get infected with COVID-19 they will develop symptoms of a common cold and get rid of the virus much quicker.

eightysixfour 6y ago
One of the known reinfections got it worse the second time, see the thread here: https://twitter.com/virusesimmunity/status/1299342270177726464?lang=en https://twitter.com/virusesimmunity/status/12993422701777264...
- soperj 6y ago
  25 year old patient, sequenced genomes of virus differed significantly. Looks like a real re-infection.
djsumdog 6y ago
Immunity is complex. Every article tries to reduce it to antibodies, but antibodies are just one aspect of "memory." Our immune systems have an inane immune system, an adaptive immune system, a Complement Protein system[0], with hundreds of thousands of proteins that have evolved over millions of years to change shape and form to grab onto and destroy all kinds of bacteria and viruses in the most random/crazy ways possible (It's a lot like microservices, except random monkeys throwing code at a wall and eventually making things work over millions of years), and many many other pieces. Every vaccine we have today is either based off an inactivated virus or an attenuated virus (a virus moved though hosts to be less lethal to humans). The first vaccine used HorsePox/CowPox to create immune memory for SmallPox by Jenner, 185 years ago. A lot of these newer vaccines like mNRA vaccines, are not vaccines at all. They attempt to generate antibodies specifically. But there could be hundreds of other interactions that occur when a virus enters your system, that can help build immunity. There's a lot we simply do not know about. Attempts at SARS1/MERS vaccines led to Imunopathic responses and Immune Enhancement Syndrome. Vaccines are some carefully engineered, invention of science. They came about due to horrific diseases, where doctors tested and experimented on human beings because thousands were going blind, getting paralyzed or dying. The rush to create a vaccine, with methods that have never successfully created a vaccine before, should be of great concern to everyone. [0]: https://www.youtube.com/watch?v=BSypUV6QUNw https://www.youtube.com/watch?v=BSypUV6QUNw

eightysixfour 6y ago

One of the known reinfections got it worse the second time, see the thread here: https://twitter.com/virusesimmunity/status/1299342270177726464?lang=en https://twitter.com/virusesimmunity/status/12993422701777264...

soperj 6y ago
25 year old patient, sequenced genomes of virus differed significantly. Looks like a real re-infection.

djsumdog 6y ago

Immunity is complex. Every article tries to reduce it to antibodies, but antibodies are just one aspect of "memory." Our immune systems have an inane immune system, an adaptive immune system, a Complement Protein system[0], with hundreds of thousands of proteins that have evolved over millions of years to change shape and form to grab onto and destroy all kinds of bacteria and viruses in the most random/crazy ways possible (It's a lot like microservices, except random monkeys throwing code at a wall and eventually making things work over millions of years), and many many other pieces. Every vaccine we have today is either based off an inactivated virus or an attenuated virus (a virus moved though hosts to be less lethal to humans). The first vaccine used HorsePox/CowPox to create immune memory for SmallPox by Jenner, 185 years ago. A lot of these newer vaccines like mNRA vaccines, are not vaccines at all. They attempt to generate antibodies specifically. But there could be hundreds of other interactions that occur when a virus enters your system, that can help build immunity. There's a lot we simply do not know about. Attempts at SARS1/MERS vaccines led to Imunopathic responses and Immune Enhancement Syndrome. Vaccines are some carefully engineered, invention of science. They came about due to horrific diseases, where doctors tested and experimented on human beings because thousands were going blind, getting paralyzed or dying. The rush to create a vaccine, with methods that have never successfully created a vaccine before, should be of great concern to everyone. [0]: https://www.youtube.com/watch?v=BSypUV6QUNw https://www.youtube.com/watch?v=BSypUV6QUNw