Proponents of intermittent fasting seem to think it's more than just calorie restriction having an effect. I would think it would be useful to isolate why the t

Proponents of intermittent fasting seem to think it's more than just calorie restriction having an effect. I would think it would be useful to isolate why the treatment works. Although I can also see why a clinical trial of a treatment would need to test the treatment as it would be applied in the real world, as opposed to a modified version intended to extract the why.