Personally I wouldn't go that high without talking to a doctor. There are just a whole bunch of confounding factors with Vitamin D: It takes six weeks of contin

Personally I wouldn't go that high without talking to a doctor. There are just a whole bunch of confounding factors with Vitamin D: It takes six weeks of continuous supplementation to really see the effects. It's fat-soluble so whether you're losing or gaining weight matters. And now this! There's just a whole lot of variables. If you're going really high-dose, check with your doctor. Even if you do need a high dose to catch up and level out, how would you know when to stop? Search the string "devaboone" here on HN for more about the potential drawbacks of really high doses.