5 ms·
Vitamin D at least 30 ng/mL reduced risk for Covid-19 adverse outcomes
- tyingq 6y agoHow do they net out the idea that people with healthy lifestyles would be less likely to have a vitamin D deficiency? (Better diet, more exposure to sunlight)
- aplummer 6y agoThey measure obesity and find it 0.02 vs 0.01 for vitamin d, which seems a decent enough proxy for lifestyle for this kind of study so your underlying point is valid here. Actually i think the biggest missing control is race. I went in skeptical even though intuitively being deficient in vitamin d makes sense, this isn’t convincing but I agree with with their conclusion that it’s worth a bigger study. If someone reading is wondering whether to maintain a healthy level of vitamin D to help if you get covid, yes you should. Should have done that before this study ofc.
- deleted 6y ago[deleted]
- cameldrv 6y agoThere was an actual randomized trial that came out recently [1] where hospitalized patients were given extremely large doses of Vitamin D (explanation of equvalent doses [2]) and it dramatically reduced ICU admission. This supports the idea that Vitamin D helping with COVID is probably causal rather than just a correlation. [1] https://www.sciencedirect.com/science/article/pii/S0960076020302764 https://www.sciencedirect.com/science/article/pii/S096007602... [2] https://chrismasterjohnphd.com/covid-19/finally-confirmed-vitamin-d-nearly-abolishes-icu-risk-in-covid-19 https://chrismasterjohnphd.com/covid-19/finally-confirmed-vi...
- yokaze 6y agoOne should not leave out the important part "pilot study". As said by the authors in the conclusions themselves, it still requires a larger one to give definite answer.
- cameldrv 6y agoI agree that a larger N would be preferable, but the effect size was enormous, and so the P value was <.001. Therefore, IMO, it's very likely that Vitamin D has a causal effect. Given that Vitamin D has at least some causal effect, it's much more likely that the observational studies that show a correlation are due to causation.
- DarknessFalls 6y agoI would be interested to know if supplementation with Vitamin D + Vitamin K2 is more effective in improving survivability.
- techsin101 6y agohow much IU is this?