My wife was in the same situation as yours and was under Tysabri for many years (10 I think). Then she got the JC virus and had to stop (she was given a choice

My wife was in the same situation as yours and was under Tysabri for many years (10 I think). Then she got the JC virus and had to stop (she was given a choice but decided to stop). She moved to Gylenia and so far so good (or at least as good as someone can be with MS). When she was diagnosed 12 years ago it was the beginning of "modern" MS treatments. 10 years back and it would have been disastrous. In 10 years there may be wonderful advancements. I feel that 100-12 years ago was a true milestone.