Well unlike LSD which is a partial agonist, 25i-NBOMe is a full, irreversible agonist that can be lethal in the event of an overdose. It really wasn't designed

Well unlike LSD which is a partial agonist, 25i-NBOMe is a full, irreversible agonist that can be lethal in the event of an overdose. It really wasn't designed for use as a recreational drug. It's history of discovery (as well as the 2C variants) was extremely interesting though.