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My point is that that the argument you made - i.e. that lower transmissibility aka. "flatten the curve" lowers total mortality in the SIR model - doesn't hold u
by sigotirandolas 6y ago
My point is that that the argument you made - i.e. that lower transmissibility aka. "flatten the curve" lowers total mortality in the SIR model - doesn't hold unless you assume that you can keep transmissibility down forever (and unless a vaccine or treatment comes out fast enough). That is, I'm not presenting a new argument, merely refuting your argument, over the SIR model you used, adding the assumption that transmissibility can't be kept down indefinitely - which I believe is very reasonable given what we are observing.
I believe it's the burden of the proof is on you to present a new, more rigorous model if you want to argue that slowing down transmission significantly lowers overall mortality - as the null hypothesis is that they are not associated.
On the last point, I am aware that under the SIR model, there's the possibility of overshoot, i.e. exceeding the minimum herd immunity threshold. My understanding is that this isn't a significant effect unless you have uncontrolled, explosive expansion, so that most people get infected simultaneously before others develop immunity and can therefore act as a barrier for herd immunity. I don't believe this is the situation right now given the numbers we are seeing.
That said, I believe that the more realistic future is that a vaccine or an effective treatment will be developed in the next months, and that will be the thing that will have made temporarily lowering transmissibility worth it. What I don't believe, because I haven't found any evidence for it that holds basic scrutiny, is that if no vaccine or effective treatment can be developed in a reasonable timeframe, then keeping the measures to slow down transmission as long as possible will have any significant effect on lower overall mortality.
EDIT: To make it clear so people do not misunderstand me, what I believe has no evidence is that without a timely vaccine or effective treatment, slowing down transmission beyond what is necessary to keep the health system from overloading is associated with lower overall mortality.
- eesmith 6y agoThe argument I make is that jb775's assertion at https://news.ycombinator.com/item?id=24586075 https://news.ycombinator.com/item?id=24586075 ("People seem to forget that the expected total death count from day 1 was, and still is, expected to be the same no matter what actions taken") is wrong. I say it's wrong because months ago I heard arguments that models predicted that lowering the curve could also reduce total mortality. And I linked to that video to give evidence that this was part of the general discussion months ago. The fact that you disagree with that model, or argue that I need to give a stronger evidence for the current information we have, has no bearing on my point. Eg, when you write "I don't believe this is the situation right now" - that statement is based on knowledge you have now, not knowledge that people had on "day 1".
- sigotirandolas 6y agoFair enough, I understand your point better now. I also remember hearing a lot of arguments for lowering the curve lowering overall deaths back in March - either by heavily suppression or elimination of spread, or by a vaccine or effective treatment. Nowadays it seems both EU & US hasn't pursued heavy suppression (probably too costly, and legally and culturally difficult), but rather just hoping to keep it somewhat under control until a vaccine comes, hopefully.