3 ms·
Calorie restriction traced back to protein/methionine restriction. Better to just fast and take melatonin (sustained-release). 16:8, 18:6, 20:4, 24:24, 36:12, 3
by baccheion 6y ago
Calorie restriction traced back to protein/methionine restriction. Better to just fast and take melatonin (sustained-release). 16:8, 18:6, 20:4, 24:24, 36:12, 36:36, etc. I am biased toward 36:36.
1-2 extended fasts per year.
I am wondering about another approach involving a bumping up of protein (0.75 g/lb for 2 days, 1.00 g/lb for 2 days, and 1.25 g/lb for 2 days) and a 42-hour dry fast wrapped around the 7th day. Melatonin (and calories missing on the 7th day) would be taken on the 6 feeding days. Last meal 3-4 hours before bed either way. The fast resensitizes to protein, same as happens when it's bumped up on 3rd days.
While many cry out against mTOR, it is responsible for synthesis of many relevant proteins: creatine, glycine, collagen, etc. The issue is more with mTOR being out of balance with AMPK. Melatonin and dry fasting helps restore the balance.
Ideally, one would increase IGF-1 as much as could be done naturally (ie, vitamins/minerals and eating frequency rather than excess protein or direct supplementation). DHEA, melatonin/progesterone, and hGH would then be adjusted to match the associated growth/pubertal year (eg, matching hormone levels of a 15 year old).