You're right maybe it can't be done universally. But you could add an optimizer to a production build system which rewrites any instance of: window.Library.

You're right maybe it can't be done universally. But you could add an optimizer to a production build system which rewrites any instance of: window.Library.util.add() To: var window_Library_util_add = window.Library.util.add; window_Library_util_add();