React and Vue can both be used directly with script tags, however the biggest difference is that React uses JSX while Vue uses HTML templates (but also supports

React and Vue can both be used directly with script tags, however the biggest difference is that React uses JSX while Vue uses HTML templates (but also supports JSX). 99% of the time, HTML is easier and faster to write, with the built-in directives providing all the functionality you need. More importantly though, HTML can be generated by every single server-side framework, and this makes it very easy to have server-side code from any language stack that becomes interactive using a Vue client-side layer.