Out of interest, are there particular platform(s) you have in mind? I remember working with TI C5x DSPs which had 16-bit "bytes", but that was a long time ago.

Out of interest, are there particular platform(s) you have in mind? I remember working with TI C5x DSPs which had 16-bit "bytes", but that was a long time ago. I'm curious whether there are still important embedded platforms that you might target with C and have unusual addressable word sizes.