I've probably had a dozen people with glasses use my headset. None of them seemed to have any issues with visual quality, though a couple had issues with comfor

I've probably had a dozen people with glasses use my headset. None of them seemed to have any issues with visual quality, though a couple had issues with comfort. The Quest comes with a spacer for glasses. That works fine 90% of the time, but some people's glasses are too big and can hit the lenses in the headset. This can be uncomfortable and (more importantly) it can scratch the lenses in the headset. If you have glasses, I'd recommend getting some lens protectors for the headset. They're usually around $10 and take a minute to apply.