2 ms·
interesting quote from the article: The mechanism by which ABO is associated with COVID-19 is unclear, but ABO blood groups can play a direct role in pathogen
by andrekandre 6y ago
interesting quote from the article:
The mechanism by which ABO is associated with COVID-19 is unclear, but ABO blood groups can play a direct role in pathogen infection by serving as receptors and/or coreceptors.
Differential glycosylation of the spike protein or the envelope glycolipids from expression of different ABO glycosyltransferases may then impact the binding and internalization of SARS-CoV-2 viral particles. Others have speculated that the lower susceptibility of blood group O could be linked to anti-A blood antibodies inhibiting the adhesion of coronavirus to ACE2-expressing cells, thereby providing protection