So one thought I had just now: If an asexual organism has both a good and a bad mutation they are intrinsically tied together forever. But with sexual reproduct

So one thought I had just now: If an asexual organism has both a good and a bad mutation they are intrinsically tied together forever. But with sexual reproduction, chromosome crossover can produce offspring having the good mutation that are also free of the bad one. Maybe we could clean up the off-target mutations using that. Edit: To clarify, I mean somehow inducing crossover in a petri-dish.