There was also an ancillary study to VITAL that focused on looking at depression & vitamin D3. Here's some good commentary on that study: https://peterattiamd.

There was also an ancillary study to VITAL that focused on looking at depression & vitamin D3. Here's some good commentary on that study: https://peterattiamd.com/randomized-controlled-trials-when-the-gold-standard-leaves-you-with-fools-gold/ https://peterattiamd.com/randomized-controlled-trials-when-t... tl;dr Due to the study's flawed design, you can't claim there's no connection between depression and oral vitamin D3 supplementation.