YES! Most of them should definitely not be daily. My own rules: marijuana: not more than once per month (I don't use it as a medicine, so once a month is fine

YES! Most of them should definitely not be daily. My own rules: marijuana: not more than once per month (I don't use it as a medicine, so once a month is fine for me) mescaline: not more than once per month (low dose, 3 to 6 teaspoons of dried san pedro powder on a saturday) psilocybin: not more than once per month (low dose below 3 grams) psilocybin: not more than once every 6 months (high dose above 3 grams) dmt: not more than once every 6 months (not smoke, must be in ritual setting with a shaman person) impepho: not more than once a month (typically once every 3 months because of the smell) caffeine: not more than once per week nicotine/alcohol: don't use. All of them are better when in nature and away from work/stress. Do not try to use them to get away from stress or to make you feel better. Feel better first, then use them. I also want to say, don't cross-use them: if you've taken one of the above, wait the same amount of time to pass before using something with similar time: meaning if you use mescaline this month, wait a month before you try marijuana; if you used high dose psilocybin recently, wait 6 months before touching dmt. Reasoning: some of them take time and their effect last longer than the day or two after dosing. Sometimes it's a week, sometimes it's 6 months. I would also not recommend combining them in the same setting or using them when you are on chronic medications (from a Dr) due to unpredictable interactions that may or may not be safe. So the idea of using LSD daily like people are popping normal pills.. probably not a good idea at all.