3 ms·
Interesting concept. One of my favorite mutations in humans is a single nucleotide flip that confers 19% improvement in working memory capacity. Substantially u
by kanzure 6y ago
Interesting concept. One of my favorite mutations in humans is a single nucleotide flip that confers 19% improvement in working memory capacity. Substantially underrated. Would only work on embryos, of course.
- AlexCoventry 6y agoWhich nucleotide site is that?
- kanzure 6y agoIt's on my list: https://diyhpl.us/wiki/genetic-modifications/ https://diyhpl.us/wiki/genetic-modifications/ rs17070145 in KIBRA/WWC1
- AlexCoventry 6y agoFrom a 2006 GWAS on 351 subjects? I would give 100-to-1 against this panning out as a causal association. Also, this was done with very low-resolution genotyping. Even if it's a genuine association, rs17070145 is probably not the causal variant, just something which is in linkage disequilibrium with it.
- Metacelsus 6y agoCitation?
- kanzure 6y ago(cite given above)