4 ms·

Depends on your definition of "significant". That's a tremendous amount of lifelong morbidity that will affect those children around the world. They may need he

Depends on your definition of "significant". That's a tremendous amount of lifelong morbidity that will affect those children around the world. They may need heart transplants, multiple surgeries, hospitalizations, etc. Just because it won't affect a lot of people doesn't suddenly make it insignificant.

GhostVII 6y ago
When I say it is insignificant, I'm saying that it is not nearly as big of a problem as the other risks from COVID. When a million people have died from COVID, and millions of children have been infected with COVID, I view any COVID symptom that affects less than 1000 people worldwide as insignificant relative that. Now it is very possible that we will realize that over the period of years, some significant percentage of children with COVID are affected by this. But so far the data doesn't support this.
- mgleason_3 6y ago
  This article appears to be a summary of the original paper. But, it leaves out some critical points - i.e.: - The papers "Discussion" section concludes with: "MIS-C is rare but the potential long-term sequelae from this disease are currently unknown." Also, the fact that it says: - ”Children might have no symptoms, no one knew they had the disease, and a few weeks later, they may develop this exaggerated inflammation in the body.“ and then a few sentences later - "...100% had fever, 73.7% had abdominal pain or diarrhea, and 68.3% suffered vomiting." Seems contradictory.
  - claudeganon 6y ago
    It’s not contradictory. The children experienced none of the typical COVID symptoms during their initial infection, which present themselves in 2-14 days. Hence, they’re categorized “asymptomatic.” Subsequent to the infection (3-4 weeks), they develop MIS-C, which manifests with the cited symptoms.
300bps 6y ago
Just because it won't affect a lot of people doesn't suddenly make it insignificant. It makes it put into context. Literally any virus, bacteria, fungi or parasite can cause myocarditis. There are about 200,000 cases of it per year. https://www.mayoclinic.org/diseases-conditions/myocarditis https://www.mayoclinic.org/diseases-conditions/myocarditis My friend’s eight year old daughter had a cold about 9 years ago that turned into myocarditis. A year on the heart transplant list using some unapproved device from Mexico to assist her heart beating, the a heart transplant, then rejection a couple years later and then a second heart transplant. From a cold.
- iancmceachern 6y ago
  I'm curious. I'm not aware of any ECMO or LVADS designed or made in Mexico. Do you know what it was called?

GhostVII 6y ago

When I say it is insignificant, I'm saying that it is not nearly as big of a problem as the other risks from COVID. When a million people have died from COVID, and millions of children have been infected with COVID, I view any COVID symptom that affects less than 1000 people worldwide as insignificant relative that. Now it is very possible that we will realize that over the period of years, some significant percentage of children with COVID are affected by this. But so far the data doesn't support this.

mgleason_3 6y ago
This article appears to be a summary of the original paper. But, it leaves out some critical points - i.e.: - The papers "Discussion" section concludes with: "MIS-C is rare but the potential long-term sequelae from this disease are currently unknown." Also, the fact that it says: - ”Children might have no symptoms, no one knew they had the disease, and a few weeks later, they may develop this exaggerated inflammation in the body.“ and then a few sentences later - "...100% had fever, 73.7% had abdominal pain or diarrhea, and 68.3% suffered vomiting." Seems contradictory.
- claudeganon 6y ago
  It’s not contradictory. The children experienced none of the typical COVID symptoms during their initial infection, which present themselves in 2-14 days. Hence, they’re categorized “asymptomatic.” Subsequent to the infection (3-4 weeks), they develop MIS-C, which manifests with the cited symptoms.

300bps 6y ago

Just because it won't affect a lot of people doesn't suddenly make it insignificant. It makes it put into context. Literally any virus, bacteria, fungi or parasite can cause myocarditis. There are about 200,000 cases of it per year. https://www.mayoclinic.org/diseases-conditions/myocarditis https://www.mayoclinic.org/diseases-conditions/myocarditis My friend’s eight year old daughter had a cold about 9 years ago that turned into myocarditis. A year on the heart transplant list using some unapproved device from Mexico to assist her heart beating, the a heart transplant, then rejection a couple years later and then a second heart transplant. From a cold.

iancmceachern 6y ago
I'm curious. I'm not aware of any ECMO or LVADS designed or made in Mexico. Do you know what it was called?