For another point of comparison, what works for me is what the OP said is the worst, just moving the mouse with my finger tips. I also tried the mouse pads you

For another point of comparison, what works for me is what the OP said is the worst, just moving the mouse with my finger tips. I also tried the mouse pads you mentioned, and they caused the most issues as they put pressure directly on my wrist. What I do is... I line up the armrest of my chair with the top of the desk so they're a level surface. I adjust the height of my chair so my arm is at a 90 degree angle. My arm runs flat across the arm rest and the desk, and my palm sits on the flat mouse pad. Then, I just move my finger tips to flick the mouse 1cm in any direction for getting to different sides of the screen. For keyboards it's similar. I use a thin and flat keyboard. This way my elbow (on the armrest), forearm, palm, and finger tips are all in a straight line. If I add any type of wrist rest, then the weight all goes to the wrist instead of being distributed. Lastly, I dislike keyboards and laptops that raise the backside because they raise my finger tips and put pressure on my wrist. It feels much more natural for the fingers to be lower or equal to the wrist and palm. Anyway, just my experience. I had some discomfort for a few years, and then nothing for the past decade.