3 ms·

Can someone tell what is the equivalent dose of said calcifedol in regular D3? The article claims 0.532 mg have been used, which seems too large. From [1] I gat

by lrem 6y ago

Can someone tell what is the equivalent dose of said calcifedol in regular D3? The article claims 0.532 mg have been used, which seems too large. From [1] I gather it's about 3x more potent, meaning we are talking about equivalent of 1.596mg of D3. Or, 10000% of RDA according to [2]. Is that right? [1]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460735/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460735/ [2]: https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/ https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessiona...

graeme 6y ago
That’s about 60,000 IU? Not necessarily out of line for such interventions. In cases of deficiency doctors will often prescribe weekly doses of 50,000 I believe. Have also seen RCT on vitamin d and the flu where groups where given 250,000-500,000 IU’s in one shot. ....obviously nobody reading this should take anything near those doses without consulting a doctor and without knowing your current blood level, to be clear.
- lrem 6y ago
  Yup, 60kIU from my understanding. And here I am wondering if the 2kIU I'm doing would have any effect...
  - ac29 6y ago
    The amount used as an interventional or short term treatment can greatly exceed what is a prudent amount to take daily. Taking 50k/day long term is probably a bad idea.
    - graeme 6y ago
      No probably about it, it’s a disastrous idea.
  - graeme 6y ago
    Again: those are medical doses, given either very temporarily or in weekly/monthly doses. 2k definitely ha san effect on a daily basis. To really know, there are two things you can do: 1. Get a vitamin d test. Fairly cheap online 2. Use the dminder app to track estimated D over time from supplements and sun exposure I don’t think I was clear enough in my post: 60,000 is not a daily dose! Higher than 4000 IU daily over a long period can lead to excess, according to Deva Boone, a doctor who was posting here and wrote some articles on this topic. 60,000 is something I’ve read about where 1. A doctor wants to correct a large deficiency, and 2. Judges large, infrequent doses are best. (My guess would be for adherence) Do not, do not. Do not take anything anywhere in that range on your own. Stick to sub 4,000 for a daily doses, and ideally get a blood test.
deleted 6y ago
[deleted]

by lrem 6y ago

graeme 6y ago

That’s about 60,000 IU? Not necessarily out of line for such interventions. In cases of deficiency doctors will often prescribe weekly doses of 50,000 I believe. Have also seen RCT on vitamin d and the flu where groups where given 250,000-500,000 IU’s in one shot. ....obviously nobody reading this should take anything near those doses without consulting a doctor and without knowing your current blood level, to be clear.

lrem 6y ago
Yup, 60kIU from my understanding. And here I am wondering if the 2kIU I'm doing would have any effect...
- ac29 6y ago
  The amount used as an interventional or short term treatment can greatly exceed what is a prudent amount to take daily. Taking 50k/day long term is probably a bad idea.
  - graeme 6y ago
    No probably about it, it’s a disastrous idea.
- graeme 6y ago
  Again: those are medical doses, given either very temporarily or in weekly/monthly doses. 2k definitely ha san effect on a daily basis. To really know, there are two things you can do: 1. Get a vitamin d test. Fairly cheap online 2. Use the dminder app to track estimated D over time from supplements and sun exposure I don’t think I was clear enough in my post: 60,000 is not a daily dose! Higher than 4000 IU daily over a long period can lead to excess, according to Deva Boone, a doctor who was posting here and wrote some articles on this topic. 60,000 is something I’ve read about where 1. A doctor wants to correct a large deficiency, and 2. Judges large, infrequent doses are best. (My guess would be for adherence) Do not, do not. Do not take anything anywhere in that range on your own. Stick to sub 4,000 for a daily doses, and ideally get a blood test.

deleted 6y ago

[deleted]