3 ms·
ACE and ACE2 [1] work in tandem: > ACE2 counters the activity of the related angiotensin-converting enzyme (ACE) by reducing the amount of angiotensin-II and i
by sradman 6y ago
ACE and ACE2 [1] work in tandem:
> ACE2 counters the activity of the related angiotensin-converting enzyme (ACE) by reducing the amount of angiotensin-II and increasing Ang(1-7)
The cell/tissue tropism of SARS-CoV-2 must logically have some effect on the function of the renin–angiotensin system (RAS). What is frustrating is that these questions remain unanswered.
[1] https://en.wikipedia.org/wiki/Angiotensin-converting_enzyme_2 https://en.wikipedia.org/wiki/Angiotensin-converting_enzyme_...
[2] https://en.wikipedia.org/wiki/Pulmonary_alveolus#Type_II_cells https://en.wikipedia.org/wiki/Pulmonary_alveolus#Type_II_cel...