There's some research showing that estrogen/androgen receptor signalling plays a part in sex-differential disease severity in SARS-CoV-1 and SARS-CoV-2. Inciden

There's some research showing that estrogen/androgen receptor signalling plays a part in sex-differential disease severity in SARS-CoV-1 and SARS-CoV-2. Incidentally, i love how some suggested pharmacotherapeutic agents include, like, nonsteroidal antiandrogens, GnRHa's, straight-up estradiol, and, of all things, spironolactone. https://cancerdiscovery.aacrjournals.org/content/10/6/779 https://cancerdiscovery.aacrjournals.org/content/10/6/779 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450662/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450662/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233687/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233687/ https://journals.physiology.org/doi/full/10.1152/ajplung.00153.2020 https://journals.physiology.org/doi/full/10.1152/ajplung.001... https://www.medrxiv.org/content/10.1101/2020.08.21.20179671v1 https://www.medrxiv.org/content/10.1101/2020.08.21.20179671v... https://www.jimmunol.org/content/jimmunol/198/10/4046.full.pdf https://www.jimmunol.org/content/jimmunol/198/10/4046.full.p... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191632/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191632/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363620/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363620/ https://link.springer.com/article/10.1007/s11906-020-01073-x https://link.springer.com/article/10.1007/s11906-020-01073-x