https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928990/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928990/ > nearly 400,000 children had been inoculated with

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928990/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928990/ > nearly 400,000 children had been inoculated with Cutter polio vaccine and 250 cases of atypical paralytic polio occurred. There were also reports of the Wyeth pharmaceutical company polio vaccine causing paralysis and death in several children in the northeastern United States. 19 , 21 > It was soon discovered that some lots of Cutter and Wyeth polio vaccine were insufficiently inactivated with formalin leading to live polio virus in more than 100,000 doses. In fact, 16 lots of Cutter polio vaccine were retested and the first six lots produced were positive for live polio virus. These incidents demonstrated the lack of oversight and safeguards put into place before the vaccine was made so widely available.