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second deadlist in the natural world, not overall. a person who was poisoned had an opportunity to figure 'oh i dont feel well', went to a hospital, made it to

by nikcub 16y ago

second deadlist in the natural world, not overall. a person who was poisoned had an opportunity to figure 'oh i dont feel well', went to a hospital, made it to the hospital, and survived the real deadly biological systems don't even give you a chance to ask if that is a missile coming over the hill

jameskilton 16y ago
This was explained though, he received an aerosoled version of the drug, which was a very, very small dose, and not directly into the blood stream. Dipping a spear into one of these things then poking a living animal and that being is dead, quickly.
- nikcub 16y ago
  > he received an aerosoled version of the drug If you are talking about threat from terrorism, then as an aerosol is the only effective way to distribute it. and if you were doing that, even something simple like Sarin is an order of magnitude stronger than this stuff the agents that were being produced during the cold war by third-world countries are again stronger than sarin and probably easy to make for a small group
  - A1kmm 16y ago
    Palytoxin LD50 (rat, intravenous): 0.089 μg/kg according to http://www.ncbi.nlm.nih.gov/pubmed/19505494 http://www.ncbi.nlm.nih.gov/pubmed/19505494 Sarin LD50 (rat, intravenous): 39 μg/kg according to http://cbwinfo.com/Chemical/Nerve/GB.shtml http://cbwinfo.com/Chemical/Nerve/GB.shtml So the lethal dose of palytoxin is ~1/438th of the lethal dose of sarin.
jerf 16y ago
"a person who was poisoned had an opportunity to figure 'oh i dont feel well', went to a hospital, made it to the hospital, and survived" I am not sure what point you are trying to make with that sentence. That this proves it's not very toxic? We know how toxic it is. The LD-50 has been determined with some precision. What this would therefore prove was that his dose was low, which considering the suboptimal delivery method isn't that surprising.
- latch 16y ago
  OT: This led me to the LD-50 wiki page http://en.wikipedia.org/wiki/Median_lethal_dose#Examples http://en.wikipedia.org/wiki/Median_lethal_dose#Examples Was very interesting to see Botox requiring 2300x a smaller dose than VX.
jrockway 16y ago
a person who was poisoned had an opportunity to figure 'oh i dont feel well', went to a hospital, made it to the hospital, and survived This doesn't, specifically, mean anything about the potency of the poison. It means something about the potency and the size of the dose the guy received. There is a spectrum of possible conclusions between "huge dose and weak poison" or "tiny does and strong poison".
scythe 16y ago
>second deadlist in the natural world, not overall. The deadliest "synthetic" poison with a known toxic level is polonium-210, used in the murder of Alexander Litivenko. It comes in third to palytoxin and botulinum toxin in potency.
masklinn 16y ago
> second deadlist in the natural world, not overall. Right. Overall it's the fourth deadliest, with an L.D.50 of 300ng/kg, behind Maitotoxin (130ng/kg), Polonium 210 (10ng/kg) and Botulinum (1ng/kg). Is that supposed to make it better? > a person who was poisoned had an opportunity to figure 'oh i dont feel well', went to a hospital, made it to the hospital, and survived A person who was poisoned with a low dose of aerosolized palytoxin survived. Injected, you would not stand a chance.
- frobozz 16y ago
  > Is that supposed to make it better? If, by "it", you mean the accuracy of the headline, then yes. If, by "it", you mean the availability of the poison, then no. We live on the largest planet in our solar system, if you apply the appropriate qualification; just like this poison is the second deadliest, if you apply the appropriate qualification.

by nikcub 16y ago

jameskilton 16y ago

This was explained though, he received an aerosoled version of the drug, which was a very, very small dose, and not directly into the blood stream. Dipping a spear into one of these things then poking a living animal and that being is dead, quickly.

nikcub 16y ago
> he received an aerosoled version of the drug If you are talking about threat from terrorism, then as an aerosol is the only effective way to distribute it. and if you were doing that, even something simple like Sarin is an order of magnitude stronger than this stuff the agents that were being produced during the cold war by third-world countries are again stronger than sarin and probably easy to make for a small group
- A1kmm 16y ago
  Palytoxin LD50 (rat, intravenous): 0.089 μg/kg according to http://www.ncbi.nlm.nih.gov/pubmed/19505494 http://www.ncbi.nlm.nih.gov/pubmed/19505494 Sarin LD50 (rat, intravenous): 39 μg/kg according to http://cbwinfo.com/Chemical/Nerve/GB.shtml http://cbwinfo.com/Chemical/Nerve/GB.shtml So the lethal dose of palytoxin is ~1/438th of the lethal dose of sarin.

jerf 16y ago

"a person who was poisoned had an opportunity to figure 'oh i dont feel well', went to a hospital, made it to the hospital, and survived" I am not sure what point you are trying to make with that sentence. That this proves it's not very toxic? We know how toxic it is. The LD-50 has been determined with some precision. What this would therefore prove was that his dose was low, which considering the suboptimal delivery method isn't that surprising.

latch 16y ago
OT: This led me to the LD-50 wiki page http://en.wikipedia.org/wiki/Median_lethal_dose#Examples http://en.wikipedia.org/wiki/Median_lethal_dose#Examples Was very interesting to see Botox requiring 2300x a smaller dose than VX.

jrockway 16y ago

a person who was poisoned had an opportunity to figure 'oh i dont feel well', went to a hospital, made it to the hospital, and survived This doesn't, specifically, mean anything about the potency of the poison. It means something about the potency and the size of the dose the guy received. There is a spectrum of possible conclusions between "huge dose and weak poison" or "tiny does and strong poison".

scythe 16y ago

>second deadlist in the natural world, not overall. The deadliest "synthetic" poison with a known toxic level is polonium-210, used in the murder of Alexander Litivenko. It comes in third to palytoxin and botulinum toxin in potency.

masklinn 16y ago

> second deadlist in the natural world, not overall. Right. Overall it's the fourth deadliest, with an L.D.50 of 300ng/kg, behind Maitotoxin (130ng/kg), Polonium 210 (10ng/kg) and Botulinum (1ng/kg). Is that supposed to make it better? > a person who was poisoned had an opportunity to figure 'oh i dont feel well', went to a hospital, made it to the hospital, and survived A person who was poisoned with a low dose of aerosolized palytoxin survived. Injected, you would not stand a chance.

frobozz 16y ago
> Is that supposed to make it better? If, by "it", you mean the accuracy of the headline, then yes. If, by "it", you mean the availability of the poison, then no. We live on the largest planet in our solar system, if you apply the appropriate qualification; just like this poison is the second deadliest, if you apply the appropriate qualification.