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As a cancer biologist, separating the metabolic from the somatic causes is complicated. Yes, ultimately cancers arise from the replication of cells with mutatio

As a cancer biologist, separating the metabolic from the somatic causes is complicated. Yes, ultimately cancers arise from the replication of cells with mutations in their DNA. But our immune system is on constant lookout for such cells and kill them once identified. So in a sense cancer is a failure of the immune system, and many things can depress the immune system, including metabolism.

wonder_er 6y ago
I appreciate your response! I'm a layperson, so I am the last person qualified to give an informed response to your comment. That said, I perceive a conceptual gap between your response, and my understanding of the metabolic theory of cancer. I believe this gap exists because the 'metabolism' piece refers not to human metabolism, but cellular metabolism, specifically how mitochondria create energy. I would be thrilled and honored if you'd read "Tripping Over the Truth"[0], but I know we all live in resource-constrained environments. You're not going to read a book because a random person on HN suggested it. Because of this, and the fact that I dislike even hinting at "do unpaid labor", I am paying people to read this book. I've allocated $5000 (5% of my pre-tax annual income when working, though I'm on a sabbatical right now) to getting certain well-positioned individuals to read Tripping Over the Truth[1]. Not to force or coerce anyone into agreeing with me, but I find the general theory to be so persuasive, I wonder if others might as well. I want expert insight into this topic. Would you be willing to accept some of that "fund" and read the book? If, after reading, you'd be willing to give me a paragraph of your commentary on the book, I'd be eternally grateful. I'd pay you $500 to read the book. If $500 isn't compelling, how about $1000? I'd send half when you agree to reading it, half when done (paypal, venmo, bitcoin, whatever). I hope you're interested. My email is in my profile! [0]: https://www.goodreads.com/book/show/23496164-tripping-over-the-truth https://www.goodreads.com/book/show/23496164-tripping-over-t... [1]: https://josh.works/mike-clayville-can-have-a-huge-impact-on-cancer https://josh.works/mike-clayville-can-have-a-huge-impact-on-...

wonder_er 6y ago

I appreciate your response! I'm a layperson, so I am the last person qualified to give an informed response to your comment. That said, I perceive a conceptual gap between your response, and my understanding of the metabolic theory of cancer. I believe this gap exists because the 'metabolism' piece refers not to human metabolism, but cellular metabolism, specifically how mitochondria create energy. I would be thrilled and honored if you'd read "Tripping Over the Truth"[0], but I know we all live in resource-constrained environments. You're not going to read a book because a random person on HN suggested it. Because of this, and the fact that I dislike even hinting at "do unpaid labor", I am paying people to read this book. I've allocated $5000 (5% of my pre-tax annual income when working, though I'm on a sabbatical right now) to getting certain well-positioned individuals to read Tripping Over the Truth[1]. Not to force or coerce anyone into agreeing with me, but I find the general theory to be so persuasive, I wonder if others might as well. I want expert insight into this topic. Would you be willing to accept some of that "fund" and read the book? If, after reading, you'd be willing to give me a paragraph of your commentary on the book, I'd be eternally grateful. I'd pay you $500 to read the book. If $500 isn't compelling, how about $1000? I'd send half when you agree to reading it, half when done (paypal, venmo, bitcoin, whatever). I hope you're interested. My email is in my profile! [0]: https://www.goodreads.com/book/show/23496164-tripping-over-the-truth https://www.goodreads.com/book/show/23496164-tripping-over-t... [1]: https://josh.works/mike-clayville-can-have-a-huge-impact-on-cancer https://josh.works/mike-clayville-can-have-a-huge-impact-on-...