It's probably fine to leave Apache or Nginx with multiple threads (probably even a good idea) but you need to make sure that uwsgi or whatever Python server you

It's probably fine to leave Apache or Nginx with multiple threads (probably even a good idea) but you need to make sure that uwsgi or whatever Python server you're using on the backend only has one process. If you can somehow architect things so a single process is doing writes (but leave multiple processes doing reads) that's likely even better. However I would suggest doing a lot of testing. It's possible multiple write processes isn't the end of the world below some threshold.