12 ms·
IMHO there are far bigger differences in how the different pipelines approach very basic things such as how to identify which parts of one person's brain corres
by fluidcruft 6y ago
IMHO there are far bigger differences in how the different pipelines approach very basic things such as how to identify which parts of one person's brain corresponds to which part of a different person's brain and what sorts of corrections should be applied for the distortions. There's a lot of stuff done that "looks good" or based on analogy (for example by assuming the brain is essentially a block of jello or a fluid) or because a particular structure is needed for a type of desired analysis (i.e. the need for an invertible displacement field) that don't necessarily have any biologic basis. There's also the issue that some people just don't have "extra" or "missing" cortical folds depending on your perspective. Additionally a real problem in general is we can't really see enough of the microstructure of the brain with enough detail to see basic things that are seem to relate to processing capabilities like the cortical layer structure without histology.