For opiates a UK study found that people eventually get bored of them and quit. For other drugs it is not necessarily clear, but other experiments exist indicat

For opiates a UK study found that people eventually get bored of them and quit. For other drugs it is not necessarily clear, but other experiments exist indicating it is likely the same. E.g. mice will intentionally go through withdrawals when there are enough resources available to procreate and other mice present.